Customization: | Available |
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Certification: | ISO, FDA |
Assay Method: | HPLC, UV |
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Product Description
Product Name: Hops Extract
Botanical Name: Humulus lupulus
Part Used: Flower
Specification
Extract Ratio: 4:1 to 20:1
5%-20% Flavones
5%, 10% 90% 98% Xanthohumol
Cas number: 6754-58-1
Molecular Formula: C21H22O5
Molecular Weight: 354.4
Function
1. Cancer prevention
1). Inducing cell apoptosis: Xanthohumol can promote apoptosis of gastric cancer cells by inducing the production of reactive oxygen species (ROS) and inhibiting the NF-κB and PI3K/Akt/mTOR pathways. It can also promote apoptosis of NCI-H460 lung cancer cells by activating the pro-apoptotic protein Bax and inhibiting the expression of the anti-apoptotic protein Bcl-2.
2). Anti-angiogenesis: Xanthohumol activates the AMPK pathway, reduces the NO level in endothelial cells, inhibits angiogenesis, and thus inhibits tumor growth and metastasis.
3). Inducing cell pyroptosis: Xanthohumol can inhibit the proliferation and migration of SGC-7901 cells, and induce cell pyroptosis by increasing the expression of GSDME-N protein.
2. Antioxidant
Xanthohumol can scavenge reactive oxygen species, inhibit the production of superoxide anion free radicals and nitric oxide, thereby reducing the damage of oxidative stress to cells.
3. Anti-inflammatory
Xanthohumol inhibits the activity of COX-1 and COX-2, reduces the production of inflammatory mediators, and has anti-inflammatory effects.
4. Antimicrobial
Xanthohumol has excellent inhibitory effects on Rhizoctonia solani and Botrytis cinerea, and can be used to prepare agricultural fungicides.
5. Antiviral
Xanthohumol has antiviral activity against a range of DNA and RNA viruses, including anti-HIV-1 activity.
Application
1. Applied in food field, adding brewing beer hops extact when brewing beer, due to its volatile oil so it has fragrant odor, and having antiseptic effect;
2. Applied in health product field,brewing beer hops extract to be made into capsule can effective relieve the tension of menopause, upset, anxiety and other symptoms.
Technical Specification
Item
|
Specification
|
Result |
Method |
Maker Compounds |
NLT 2%Xanthohumol |
2.14% |
HPLC |
Identification |
Complies by TLC |
Complies |
TLC |
Organoleptic |
|||
Appearance |
Brown Powder |
Brown Powder |
Visual |
Color |
Brown |
Brown |
Visual |
Odor |
Characteristic |
Characteristic |
Organoleptic |
Taste |
Characteristic |
Characteristic |
Organoleptic |
Method of Extraction |
Soak and Extraction |
N/A |
N/A |
Extraction Solvents |
Water&Alcohol |
N/A |
N/A |
Excipient |
None |
N/A |
N/A |
Physical Characteristics |
|||
Particle Size |
NLT100%Through 80 mesh |
100% |
USP < 786 > |
Loss on Drying |
≤5.00% |
1.02% |
Draco method 1.1.1.0 |
Bulk Density |
40-60g/100ml |
52.5g/100ml |
Packing & Delivery
Delivery:
Sea/Air Shipping & International Express
According to quantity and customer requirements
Shipping Time:
Within a week after payment
Package:
1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 35cm (Diameter)*51cm (Height)
Storage:
Kept away from strong light and heat.
Shelf Life:
24 months
Our service
1.Free sample
2.Owning cultivation base as 100% Natural material stable source.
3.Manufacturer direct supply, Powerful R&D team and advanced test center
4.Leading plant extract manufacturer in China.
5.No excuse return of goods
6.OEM & ODM is available