| Customization: | Available |
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| Certification: | ISO, FDA |
| Assay Method: | HPLC, UV |
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English Name: 3,3'-Diindolylmethane
Other Name: 3-(1H-Indol-3-ylmethyl)-1H-indole; 3,3'-Methylenebis-1H-indole; DIM
Appearance: White or almost white powder
CAS No.: 1968-05-4
Molecular formula: C17H14N2
Function
Abnormal growth of cells of the cervix (cervical dysplasia). Early research suggests that taking a specific diindolylmethane product (BioResponse-DIM by BioResponse) for 12 weeks does not improve markers of disease in women with cervical dysplasia.
Prostate cancer. Early research suggest that taking a specific diindolylmethane product (BioResponse-DIM) for 28 days lowers prostate-specific antigen (PSA) levels in men with prostate cancer. PSA levels can be used to measure the Progress of prostate cancer.
Abnormal growth of cells of the cervix (cervical dysplasia). Early research suggests that taking a specific diindolylmethane product (BioResponse-DIM by BioResponse) for 12 weeks does not improve markers of disease in women with cervical dysplasia.
Preventing uterine cancer.
Preventing colon cancer.
Preventing breast cancer.
Preventing prostate enlargement (benign prostatic hypertrophy, BPH).
Treating premenstrual syndrome (PMS).
Other conditions.
Application
1. Combats Cancer
DIM is potent at fighting cancer.
For example, DIM inhibited the growth of mammary gland cell cancer, (via modulation of estrogen receptor α and AhR).
2. Reduces Inflammation
As a partial CB2 agonist, DIM may help with neuroinflammation by working on the endocannabinoid system. DIM can also protect against inflammation by acting on GPR84.DIM also has potent COX-2 inhibition properties.
3.Promotes Detoxification And Antioxidant Production
Through the activation of Aryl Hydrocarbon Receptors (AhR) and Nrf2 signaling pathways, DIM effectively increases detoxification and reduces inflammatory signaling
DIM can modulate AhR, which promotes transcription of genes that stimulate the expression of detoxification enzymes, including the phase I cytochrome P450 (CYP) family. It can also induce the transcription factor NRF2, which has strong anti-oxidant and detoxification properties.
| Content | Specification |
| Appearance | Off-white to light yellow Powder |
| Assay(HPLC) | ≥99% |
| Melting Point | 96 -100°C |
| Loss on drying | ≤5.0% |
| Residual on Ignition | ≤0.5% |
| Bulk density (loose) | 0.15-0.45g/ml |
| Arsenic | ≤1ppm |
| Pb | ≤5ppm |
| Microbiological Control | |
| Total Plate Count | <500CFU/G |
| Mould &Yeast | <100CFU/G |
| E.Coli | Absent |
| Salmonella | Absent |
| Stahylococcus aureus | Absent |
| Pseudomona aeruginosa | Absent |
Package :
Delivery:Sea/Air Shipping & International Express
Shipping Time:15 working days after payment
Package: 1-5kg/Aluminum foil bag, size: 22cm (Width)*32cm (Length)
15-25kg/Drum, size: 35cm (Diameter)*51cm (Height)
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
Our service :
1.Free sample
2.Owning cultivation base as 100% Natural material stable source.
3.Manufacturer direct supply, Powerful R&D team and advanced test center
4.Leading plant extract manufacturer in China.
5.No excuse return of goods
6.OEM & ODM is available
FAQ
Q&A
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
Q4: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q5: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer.
In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment
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